It could be done. The thing that would worry me if I were to do that persoanlly. Is for the power suply since I don't know off hand it uses the same connection as the regular IBM PC and their clones. And the second is that I would have to open it up to see if where you have he added cards that come out like video, nic, will fit the same area down below. it hard to judge on things like this. Unless you going to make some modifications to the casing itself to make it possible. A Modd version of a mac but runs Ibm parts.:Good would be different to see.